Anti-Recombinant-ADRA1A antibody [RM1U96] (STJA0024476)

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STJA0024476
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC/IF/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Alpha-1a Adrenergic Receptor is suitable for use in Flow Cytometry, Immunofluorescence and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1U96
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ADRA1A
Gene ID: 148
Uniprot ID: ADA1A_HUMAN
Post Translational Modifications C-terminal Ser or Thr residues may be phosphorylated.
Function This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Protein Name Alpha-1a Adrenergic Receptor
Alpha-1a Adrenoreceptor
Alpha-1a Adrenoceptor
Alpha-1c Adrenergic Receptor
Alpha-Adrenergic Receptor 1c
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-416476
Reactome: R-HSA-416482
Cellular Localisation Nucleus Membrane
Multi-Pass Membrane Protein
Cell Membrane
Cytoplasm
Membrane
Caveola
Location At The Nuclear Membrane Facilitates Heterooligomerization And Regulates Erk-Mediated Signaling In Cardiac Myocytes
Colocalizes With Gnaq
Plcb1 As Well As Lap2 At The Nuclear Membrane Of Cardiac Myocytes
Alternative Antibody Names Anti-Alpha-1a Adrenergic Receptor antibody
Anti-Alpha-1a Adrenoreceptor antibody
Anti-Alpha-1a Adrenoceptor antibody
Anti-Alpha-1c Adrenergic Receptor antibody
Anti-Alpha-Adrenergic Receptor 1c antibody
Anti-ADRA1A antibody
Anti-ADRA1C antibody

Information sourced from Uniprot.org

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