• Western blot analysis of lysates from Raji cells, using RASSF2 Rabbit polyclonal antibody (STJ118211) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s.

Anti-RASSF2 antibody (70-160) (STJ118211)

SKU:
STJ118211

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RASSF2 (70-160) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RASSF2
Gene ID: 9770
Uniprot ID: RASF2_HUMAN
Immunogen Region: 70-160
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_055552.1).
Immunogen Sequence: MQDDNERIRPPPSSSSWHSG CNLGAQGTTLKPLTVPKVQI SEVDAPPEGDQMPSSTDSRG LKPLQEDTPQLMRTRSDVGV RRRGNVRTPSD
Tissue Specificity Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Post Translational Modifications Phosphorylated by STK3/MST2 and STK4/MST1.
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Protein Name Ras Association Domain-Containing Protein 2
Cellular Localisation Nucleus
Cytoplasm
Chromosome
Centromere
Kinetochore
Translocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1
Alternative Antibody Names Anti-Ras Association Domain-Containing Protein 2 antibody
Anti-RASSF2 antibody
Anti-CENP-34 antibody
Anti-KIAA0168 antibody

Information sourced from Uniprot.org

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