| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAP1GAP (508-727) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAP1GAP |
| Gene ID: |
5909 |
| Uniprot ID: |
RPGP1_HUMAN |
| Immunogen Region: |
508-727 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 508-727 of human Rap1GAP (NP_001139130.1). |
| Immunogen Sequence: |
AMGLSNKKPNTVSTSHSGSF APNNPDLAKAAGISLIVPGK SPTRKKSGPFGSRRSSAIGI ENIQEVQEKRESPPAGQKTP DSGHVSQEPKSENSSTQSSP EMPTTKNRAETAAQRAEALK DFSRSSSSASSFASVVEETE GVDGEDTGLESVSSSGTPHK RDSFIYSTWLEDSVSTTSGG SSPGPSRSPHPDAGKLGDPA CPEIKIQLEASEQHMPQLGC |
| Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. |
| Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
| Protein Name | Rap1 Gtpase-Activating Protein 1Rap1gapRap1gap1 |
| Database Links | Reactome: R-HSA-392517Reactome: R-HSA-8853659 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap1 Gtpase-Activating Protein 1 antibodyAnti-Rap1gap antibodyAnti-Rap1gap1 antibodyAnti-RAP1GAP antibodyAnti-KIAA0474 antibodyAnti-RAP1GA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
