• Immunohistochemistry of paraffin-embedded mouse spinal cord using RAB4A rabbit polyclonal antibody (STJ115501) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry of paraffin-embedded mouse stomach using RAB4A rabbit polyclonal antibody (STJ115501) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunofluorescence analysis of NIH/3T3 cells using RAB4A rabbit polyclonal antibody (STJ115501) at dilution of 1:150 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of PC-12 cells using RAB4A rabbit polyclonal antibody (STJ115501) at dilution of 1:150 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of U2OS cells using RAB4A rabbit polyclonal antibody (STJ115501) at dilution of 1:150 (40x lens). Blue: DAPI for nuclear staining.

Anti-RAB4A antibody (50-150) (STJ115501)

SKU:
STJ115501

£169.50 - £449.50
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Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RAB4A (50-150) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB4A
Gene ID: 5867
Uniprot ID: RAB4A_HUMAN
Immunogen Region: 50-150
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RAB4A (NP_004569.2).
Immunogen Sequence: FGSKIINVGGKYVKLQIWDT AGQERFRSVTRSYYRGAAGA LLVYDITSRETYNALTNWLT DARMLASQNIVIILCGNKKD LDADREVTFLEASRFAQENE L
Post Translational Modifications Phosphorylated by CDK1 kinase during mitosis. Serotonylation of Gln-72 by TGM2 during activation and aggregation of platelets leads to constitutive activation of GTPase activity.
Function Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Involved in protein transport. Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets.
Protein Name Ras-Related Protein Rab-4a
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-1660499
Reactome: R-HSA-8854214
Reactome: R-HSA-8873719
Reactome: R-HSA-8875656
Cellular Localisation Membrane
Peripheral Membrane Protein
Cytoplasm
Early Endosome Membrane
Recycling Endosome Membrane
Generally Associated With Membranes
Cytoplasmic When Phosphorylated By Cdk1
Alternative Antibody Names Anti-Ras-Related Protein Rab-4a antibody
Anti-RAB4A antibody
Anti-RAB4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance