| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAB39A (100-170) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAB39A |
| Gene ID: |
54734 |
| Uniprot ID: |
RB39A_HUMAN |
| Immunogen Region: |
100-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 100-170 of human RAB39A (NP_059986.1). |
| Immunogen Sequence: |
SFEHVKDWLEEAKMYVQPFR IVFLLVGHKCDLASQRQVTR EEAEKLSADCGMKYIETSAK DATNVEESFTI |
| Function | Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation. |
| Protein Name | Ras-Related Protein Rab-39aRab-39 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesiclePhagosomePhagosome MembraneLysosomeRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-39a antibodyAnti-Rab-39 antibodyAnti-RAB39A antibodyAnti-RAB39 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
