| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB39A |
| Gene ID: | 54734 |
| Uniprot ID: | RB39A_HUMAN |
| Immunogen Region: | 100-170 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-170 of human RAB39A (NP_059986.1). |
| Immunogen Sequence: | SFEHVKDWLEEAKMYVQPFR IVFLLVGHKCDLASQRQVTR EEAEKLSADCGMKYIETSAK DATNVEESFTI |
| Function | Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation. |
| Protein Name | Ras-Related Protein Rab-39aRab-39 |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesiclePhagosomePhagosome MembraneLysosomeRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-39a antibodyAnti-Rab-39 antibodyAnti-RAB39A antibodyAnti-RAB39 antibody |
Information sourced from Uniprot.org