Host: | Goat |
Applications: | WB |
Reactivity: | Human/Rat/Mouse/Monkey/Canine |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-RAB20, member RAS oncogene family (130aa C-Term) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
Purification: | This antibody is epitope-affinity purified from goat antiserum. |
Concentration: | 2 mg/mL |
Dilution Range: | WB 1:250-1:2000 |
Storage Instruction: | Store at-20 C for long-term storage. Store at 2-8 C for up to one month. |
Gene Symbol: | RAB20 |
Gene ID: | 55647 |
Uniprot ID: | RAB20_HUMAN |
Immunogen Region: | 130aa C-Term |
Accession Number: | ENSG00000139832 |
Specificity: | Detects Rab20 in transfected cells with GFP-Rab20 by Western blot. Detects levels of endogenous Rab20 (testis, liver and kidney) by Western blot. |
Immunogen: | Purified recombinant peptide derived from within residues 130 aa to the C-terminus of Rab20 produced in E. coli. |
Tissue Specificity | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). |
Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. |
Protein Name | Ras-Related Protein Rab-20 |
Database Links | Reactome: R-HSA-8873719 |
Cellular Localisation | Golgi ApparatusCytoplasmic VesiclePhagosomePhagosome MembraneLipid-AnchorCytoplasmic SideHighly Enriched On Apical Endocytic Structures In Polarized Epithelial Cells Of Kidney Proximal TubulesRecruited To Phagosomes Containing SAureus Or MTuberculosis |
Alternative Antibody Names | Anti-Ras-Related Protein Rab-20 antibodyAnti-RAB20 antibody |
Information sourced from Uniprot.org