| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PTCHD1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 100kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 101kDa according to NP_775766.2). Recommended concentration: 0.5-2µg/ml.An additional band of unknown |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PTCHD1 |
| Gene ID: | 139411 |
| Uniprot ID: | PTHD1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_775766.2 |
| Immunogen Sequence: | DFQKTSRVSER |
| Function | Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. Can bind cholesterol in vitro. |
| Protein Name | Patched Domain-Containing Protein 1 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritic Spine |
| Alternative Antibody Names | Anti-Patched Domain-Containing Protein 1 antibodyAnti-PTCHD1 antibody |
Information sourced from Uniprot.org