| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSAT1 |
| Gene ID: | 29968 |
| Uniprot ID: | SERC_HUMAN |
| Immunogen Region: | 1-370 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human PSAT1 (NP_478059.1). |
| Immunogen Sequence: | MDAPRQVVNFGPGPAKLPHS VLLEIQKELLDYKGVGISVL EMSHRSSDFAKIINNTENLV RELLAVPDNYKVIFLQGGGC GQFSAVPLNLIGLKAGRCAD YVVTGAWSAKAAEEAKKFGT INIVHPKLGSYTKIPDPSTW NLNPDASYVYYCANETVHGV EFDFIPDVKGAVLVCDMSSN FLSKPVDVSKFGVIFAGAQK NVGSAGVTVVIVRDDLLGFA LRECPSVLEYKVQAGNSSL |
| Tissue Specificity | Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon. |
| Function | Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3-phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3-phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate. |
| Protein Name | Phosphoserine AminotransferasePhosphohydroxythreonine AminotransferasePsat |
| Database Links | Reactome: R-HSA-977347 |
| Alternative Antibody Names | Anti-Phosphoserine Aminotransferase antibodyAnti-Phosphohydroxythreonine Aminotransferase antibodyAnti-Psat antibodyAnti-PSAT1 antibodyAnti-PSA antibody |
Information sourced from Uniprot.org