| Host: | Rabbit |
| Applications: | IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R3C |
| Gene ID: | 5507 |
| Uniprot ID: | PPR3C_HUMAN |
| Immunogen Region: | 1-150 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PPP1R3C (NP_005389.1). |
| Immunogen Sequence: | MSCTRMIQVLDPRPLTSSVM PVDVAMRLCLAHSPPVKSFL GPYDEFQRRHFVNKLKPLKS CLNIKHKAKSQNDWKCSHNQ AKKRVVFADSKGLSLTAIHV FSDLPEEPAWDLQFDLLDLN DISSALKHHEEKNLILDFPQ PSTDYLSFRS |
| Post Translational Modifications | Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner. |
| Function | Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3cProtein Phosphatase 1 Regulatory Subunit 5Pp1 Subunit R5Protein Targeting To GlycogenPtg |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653 |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 3c antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 5 antibodyAnti-Pp1 Subunit R5 antibodyAnti-Protein Targeting To Glycogen antibodyAnti-Ptg antibodyAnti-PPP1R3C antibodyAnti-PPP1R5 antibody |
Information sourced from Uniprot.org