| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POLR2F |
| Gene ID: | 5435 |
| Uniprot ID: | RPAB2_HUMAN |
| Immunogen Region: | 1-127 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human POLR2F (NP_068809.1). |
| Immunogen Sequence: | MSDNEDNFDGDDFDDVEEDE GLDDLENAEEEGQENVEILP SGERPQANQKRITTPYMTKY ERARVLGTRALQIAMCAPVM VELEGETDPLLIAMKELKAR KIPIIIRRYLPDGSYEDWGV DELIITD |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPABC2 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. |
| Protein Name | Dna-Directed Rna Polymerases I - Ii - And Iii Subunit Rpabc2Rna Polymerases I - Ii - And Iii Subunit Abc2Dna-Directed Rna Polymerase Ii Subunit FDna-Directed Rna Polymerases I - Ii - And Iii 14.4 Kda PolypeptideRpabc14.4Rpb14.4Rpb6 HomologRpc15 |
| Database Links | Reactome: R-HSA-112382Reactome: R-HSA-113418Reactome: R-HSA-167152Reactome: R-HSA-167158Reactome: R-HSA-167160Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-167200Reactome: R-HSA-167238Reactome: R-HSA-167242Reactome: R-HSA-167243Reactome: R-HSA-167246Reactome: R-HSA-167287Reactome: R-HSA-167290Reactome: R-HSA-168325Reactome: R-HSA-1834949Reactome: R-HSA-203927Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5578749Reactome: R-HSA-5601884Reactome: R-HSA-5617472Reactome: R-HSA-674695Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6796648Reactome: R-HSA-6803529Reactome: R-HSA-6807505Reactome: R-HSA-72086Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72203Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-73780Reactome: R-HSA-73863Reactome: R-HSA-73980Reactome: R-HSA-749476Reactome: R-HSA-75953Reactome: R-HSA-75955Reactome: R-HSA-76042Reactome: R-HSA-76061Reactome: R-HSA-76066Reactome: R-HSA-76071Reactome: R-HSA-77075Reactome: R-HSA-8851708Reactome: R-HSA-9018519Reactome: R-HSA-9670095 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerases I - Ii - And Iii Subunit Rpabc2 antibodyAnti-Rna Polymerases I - Ii - And Iii Subunit Abc2 antibodyAnti-Dna-Directed Rna Polymerase Ii Subunit F antibodyAnti-Dna-Directed Rna Polymerases I - Ii - And Iii 14.4 Kda Polypeptide antibodyAnti-Rpabc14.4 antibodyAnti-Rpb14.4 antibodyAnti-Rpb6 Homolog antibodyAnti-Rpc15 antibodyAnti-POLR2F antibodyAnti-POLRF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
