| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
PLCB4 |
| Gene ID: |
5332 |
| Uniprot ID: |
PLCB4_HUMAN |
| Immunogen Region: |
1-100 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLCB4 (NP_000924.3). |
| Immunogen Sequence: |
MAKPYEFNWQKEVPSFLQEG AVFDRYEEESFVFEPNCLFK VDEFGFFLTWRSEGKEGQVL ECSLINSIRSGAIPKDPKIL AALEAVGKSENDLEGRIVCV |
| Tissue Specificity | Preferentially expressed in the retina. |
| Function | Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4Phosphoinositide Phospholipase C-Beta-4Phospholipase C-Beta-4Plc-Beta-4 |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-1855204Reactome: R-HSA-416476 |
| Cellular Localisation | Cell Membrane |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4 antibodyAnti-Phosphoinositide Phospholipase C-Beta-4 antibodyAnti-Phospholipase C-Beta-4 antibodyAnti-Plc-Beta-4 antibodyAnti-PLCB4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
