Anti-PLCB4 antibody (1-100 aa) (STJ11107148)

SKU:
STJ11107148
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: PLCB4
Gene ID: 5332
Uniprot ID: PLCB4_HUMAN
Immunogen Region: 1-100 aa
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLCB4 (NP_000924.3).
Immunogen Sequence: MAKPYEFNWQKEVPSFLQEG AVFDRYEEESFVFEPNCLFK VDEFGFFLTWRSEGKEGQVL ECSLINSIRSGAIPKDPKIL AALEAVGKSENDLEGRIVCV
Tissue Specificity Preferentially expressed in the retina.
Function Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development.
Protein Name 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4
Phosphoinositide Phospholipase C-Beta-4
Phospholipase C-Beta-4
Plc-Beta-4
Database Links Reactome: R-HSA-112043
Reactome: R-HSA-1855204
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Alternative Antibody Names Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4 antibody
Anti-Phosphoinositide Phospholipase C-Beta-4 antibody
Anti-Phospholipase C-Beta-4 antibody
Anti-Plc-Beta-4 antibody
Anti-PLCB4 antibody

Information sourced from Uniprot.org

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