Tissue Specificity | Preferentially expressed in the retina. |
Function | Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development. |
Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4Phosphoinositide Phospholipase C-Beta-4Phospholipase C-Beta-4Plc-Beta-4 |
Database Links | Reactome: R-HSA-112043Reactome: R-HSA-1855204Reactome: R-HSA-416476 |
Cellular Localisation | Cell Membrane |
Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4 antibodyAnti-Phosphoinositide Phospholipase C-Beta-4 antibodyAnti-Phospholipase C-Beta-4 antibodyAnti-Plc-Beta-4 antibodyAnti-PLCB4 antibody |
Information sourced from Uniprot.org