| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIGT |
| Gene ID: | 51604 |
| Uniprot ID: | PIGT_HUMAN |
| Immunogen Region: | 260-460 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-460 of human PIGT (NP_057021.2). |
| Immunogen Sequence: | LFRMFSRTLTEPCPLASESR VYVDITTYNQDNETLEVHPP PTTTYQDVILGTRKTYAIYD LLDTAMINNSRNLNIQLKWK RPPENEAPPVPFLHAQRYVS GYGLQKGELSTLLYNTHPYR AFPVLLLDTVPWYLRLYVHT LTITSKGKENKPSYIHYQPA QDRLQPHLLEMLIQLPANSV TKVSIQFERALLKWTEYTPD P |
| Post Translational Modifications | The disulfide bond between PIGK/GPI8 and PIGT is important for normal enzyme activity. |
| Function | Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. |
| Protein Name | Gpi Transamidase Component Pig-TPhosphatidylinositol-Glycan Biosynthesis Class T Protein |
| Database Links | Reactome: R-HSA-162791 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Gpi Transamidase Component Pig-T antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class T Protein antibodyAnti-PIGT antibodyAnti-CGI-06 antibodyAnti-PSEC0163 antibodyAnti-UNQ716 antibodyAnti-PRO1379 antibody |
Information sourced from Uniprot.org