• Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-Phospho-TGFBR3-Thr842 antibody (801-850 aa) (STJ91321)

SKU:
STJ91321

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Transforming growth factor beta receptor type 3-Thr842 (801-850 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TGFBR3
Gene ID: 7049
Uniprot ID: TGBR3_HUMAN
Immunogen Region: 801-850 aa
Specificity: Phospho-TGF Beta RIII (T842) Polyclonal Antibody detects endogenous levels of TGF Beta RIII protein only when phosphorylated at T842.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TGF beta Receptor III around the phosphorylation site of Thr842 at the amino acid range 801-850
Function Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. In gonadotrope cells, acts as an inhibin A coreceptor and regulates follicle-stimulating hormone (FSH) levels and female fertility.
Protein Name Transforming Growth Factor Beta Receptor Type 3
Tgf-Beta Receptor Type 3
Tgfr-3
Betaglycan
Transforming Growth Factor Beta Receptor Iii
Tgf-Beta Receptor Type Iii
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
Extracellular Space
Extracellular Matrix
Exists Both As A Membrane-Bound Form And As Soluble Form In Serum And In The Extracellular Matrix
Alternative Antibody Names Anti-Transforming Growth Factor Beta Receptor Type 3 antibody
Anti-Tgf-Beta Receptor Type 3 antibody
Anti-Tgfr-3 antibody
Anti-Betaglycan antibody
Anti-Transforming Growth Factor Beta Receptor Iii antibody
Anti-Tgf-Beta Receptor Type Iii antibody
Anti-TGFBR3 antibody

Information sourced from Uniprot.org

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