| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Heterogeneous nuclear ribonucleoprotein A0-Ser84 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNRNPA0 |
| Gene ID: | 10949 |
| Uniprot ID: | ROA0_HUMAN |
| Specificity: | This antibody detects endogenous levels of HNRPA0 (Phospho-Ser84) at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human HNRPA0 (Phospho-Ser84) |
| Post Translational Modifications | Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA. Arg-291 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A0Hnrnp A0 |
| Cellular Localisation | NucleusComponent Of Ribonucleosomes |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A0 antibodyAnti-Hnrnp A0 antibodyAnti-HNRNPA0 antibodyAnti-HNRPA0 antibody |
Information sourced from Uniprot.org