| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Phospho-ARAF-S299 is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARAF |
| Gene ID: | 369 |
| Uniprot ID: | ARAF_HUMAN |
| Immunogen: | A synthetic phosphorylated peptide around S299 of human ARAF (NP_001645.1). |
| Immunogen Sequence: | RDSGY |
| Tissue Specificity | Predominantly in urogenital tissues. |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation. |
| Protein Name | Serine/Threonine-Protein Kinase A-RafProto-Oncogene A-RafProto-Oncogene A-Raf-1Proto-Oncogene Pks |
| Database Links | Reactome: R-HSA-5673000Reactome: R-HSA-5674135Reactome: R-HSA-5675221Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948Reactome: R-HSA-9656223Reactome: R-HSA-9726840Reactome: R-HSA-9726842 |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase A-Raf antibodyAnti-Proto-Oncogene A-Raf antibodyAnti-Proto-Oncogene A-Raf-1 antibodyAnti-Proto-Oncogene Pks antibodyAnti-ARAF antibodyAnti-ARAF1 antibodyAnti-PKS antibodyAnti-PKS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
