| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Pescadillo (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 70kDa band observed in HeLa lysate (calculated MW of 68kDa according to NP_055118). Recommended concentration: 1-3µg/ml.IHC: In paraffin embedded Human Testis shows nucleol |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PES1 |
| Gene ID: | 23481 |
| Uniprot ID: | PESC_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_055118.1 |
| Immunogen Sequence: | GGLEKKKYERGSA |
| Post Translational Modifications | Sumoylated. |
| Function | Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. |
| Protein Name | Pescadillo Homolog |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusNucleoplasmChromosomeAppears To Localize To The Periphery Of Metaphase Chromosomes During Mitosis And To The Prenucleolar Bodies That Form In Mitotic Cells Prior To The Actual Nucleoli |
| Alternative Antibody Names | Anti-Pescadillo Homolog antibodyAnti-PES1 antibody |
Information sourced from Uniprot.org