Anti-PDHA1 antibody (STJA0010259)

SKU:
STJA0010259
£48.00 - £252.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDHA1
Gene ID: 5160
Uniprot ID: ODPA_HUMAN
Specificity: This antibody detects endogenous levels of PDHA1/2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human PDHA1/2
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylation at Ser-232, Ser-293 and Ser-300 by PDK family kinases inactivates the enzyme.for this phosphorylation at a single site is sufficient. Dephosphorylation at all three sites, i.e. at Ser-232, Ser-293 and Ser-300, is required for reactivation. Acetylation alters the phosphorylation pattern. Deacetylated by SIRT3.
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Protein Name Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial
Pdhe1-A Type I
Database Links Reactome: R-HSA-204174
Reactome: R-HSA-5362517
Reactome: R-HSA-9837999
Reactome: R-HSA-9861559
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial antibody
Anti-Pdhe1-A Type I antibody
Anti-PDHA1 antibody
Anti-PHE1A antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ11103767 Anti-Phospho-PDHA1-S293 antibody (STJ11103767) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ98528 Anti-PDHA1 antibody (C-Term) (STJ98528) Mouse Monoclonal Human/Mouse/Rat/Cow/Dog/Pig WB/IF
STJ11104401 Anti-PDHA1 antibody (30-390) (STJ11104401) Rabbit Polyclonal Human/Mouse WB/IF/ICC/IP/ELISA
STJ119549 Anti-PDHA1 antibody (30-390) (STJ119549) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/IF/ICC/ELISA
STJ24939 Anti-PDHA1 antibody (30-390) (STJ24939) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/IF/ICC/IP/ELISA
!