• Western blot analysis of extracts of various cell lines, using PDE7B antibody (STJ114028) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PDE7B antibody (341-450) (STJ114028)

SKU:
STJ114028

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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE7B
Gene ID: 27115
Uniprot ID: PDE7B_HUMAN
Immunogen Region: 341-450
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 341-450 of human PDE7B (NP_061818.1).
Immunogen Sequence: VCEEFYRQGELEQKFELEIS PLCNQQKDSIPSIQIGFMSY IVEPLFREWAHFTGNSTLSE NMLGHLAHNKAQWKSLLPRQ HRSRGSSGSGPDHDHAGQGT ESEEQEGDSP
Tissue Specificity Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
Protein Name 3' -5'-Cyclic-Amp Phosphodiesterase 7b
Camp-Specific Phosphodiesterase 7b
Database Links Reactome: R-HSA-418555
Alternative Antibody Names Anti-3' -5'-Cyclic-Amp Phosphodiesterase 7b antibody
Anti-Camp-Specific Phosphodiesterase 7b antibody
Anti-PDE7B antibody

Information sourced from Uniprot.org

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