| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PCSK2 (1-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PCSK2 |
| Gene ID: |
5126 |
| Uniprot ID: |
NEC2_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human PCSK2 (NP_002585.2). |
| Immunogen Sequence: |
MKGGCVSQWKAAAGFLFCVM VFASAERPVFTNHFLVELHK GGEDKARQVAAEHGFGVRKL PFAEGLYHFYHNGLAKAKRR RSLHHKQQLERDPRVKMALQ QEGFDRKKRGYRDINEIDIN MNDPLFTKQWYLINTGQADG TPGLDLNVAEAWELGYTGKG VTIGIMDDGIDYLHPDLASN YNAEASYDFSSNDPYPYPRY TDDWFNSHGTRCAGEVSAAA |
| Function | Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. |
| Protein Name | Neuroendocrine Convertase 2Nec 2Kex2-Like Endoprotease 2Prohormone Convertase 2Proprotein Convertase 2Pc2 |
| Database Links | Reactome: R-HSA-264876 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSecretedLocalized In The Secretion Granules |
| Alternative Antibody Names | Anti-Neuroendocrine Convertase 2 antibodyAnti-Nec 2 antibodyAnti-Kex2-Like Endoprotease 2 antibodyAnti-Prohormone Convertase 2 antibodyAnti-Proprotein Convertase 2 antibodyAnti-Pc2 antibodyAnti-PCSK2 antibodyAnti-NEC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")