| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-P2RY4 (286-365) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
P2RY4 |
| Gene ID: |
5030 |
| Uniprot ID: |
P2RY4_HUMAN |
| Immunogen Region: |
286-365 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 286-365 of human P2RY4 (NP_002556.1). |
| Immunogen Sequence: |
VVYKVTRPLASANSCLDPVL YLLTGDKYRRQLRQLCGGGK PQPRTAASSLALVSLPEDSS CRWAATPQDSSCSTPRADRL |
| Tissue Specificity | Pancreas. |
| Post Translational Modifications | Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases. |
| Function | Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. |
| Protein Name | P2y Purinoceptor 4P2y4P2pUridine Nucleotide ReceptorUnr |
| Database Links | Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 4 antibodyAnti-P2y4 antibodyAnti-P2p antibodyAnti-Uridine Nucleotide Receptor antibodyAnti-Unr antibodyAnti-P2RY4 antibodyAnti-NRU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
