| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-OSGEP (1-335) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OSGEP |
| Gene ID: |
55644 |
| Uniprot ID: |
OSGEP_HUMAN |
| Immunogen Region: |
1-335 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human OSGEP (NP_060277.1). |
| Immunogen Sequence: |
MPAVLGFEGSANKIGVGVVR DGKVLANPRRTYVTPPGTGF LPGDTARHHRAVILDLLQEA LTESGLTSQDIDCIAYTKGP GMGAPLVSVAVVARTVAQLW NKPLVGVNHCIGHIEMGRLI TGATSPTVLYVSGGNTQVIA YSEHRYRIFGETIDIAVGNC LDRFARVLKISNDPSPGYNI EQMAKRGKKLVELPYTVKGM DVSFSGILSFIEDVAHRMLA TGECTPEDLCFSLQETVFA |
| Tissue Specificity | Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas. |
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. |
| Protein Name | Trna N6-Adenosine ThreonylcarbamoyltransferaseN6-L-Threonylcarbamoyladenine SynthaseT(6a SynthaseO-Sialoglycoprotein EndopeptidaseHosgepT(6a37 Threonylcarbamoyladenosine Biosynthesis Protein OsgepTrna Threonylcarbamoyladenosine Biosynthesis Protein Osgep |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Trna N6-Adenosine Threonylcarbamoyltransferase antibodyAnti-N6-L-Threonylcarbamoyladenine Synthase antibodyAnti-T(6a Synthase antibodyAnti-O-Sialoglycoprotein Endopeptidase antibodyAnti-Hosgep antibodyAnti-T(6a37 Threonylcarbamoyladenosine Biosynthesis Protein Osgep antibodyAnti-Trna Threonylcarbamoyladenosine Biosynthesis Protein Osgep antibodyAnti-OSGEP antibodyAnti-GCPL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
