| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-OSBPL5 (550-790) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OSBPL5 |
| Gene ID: |
114879 |
| Uniprot ID: |
OSBL5_HUMAN |
| Immunogen Region: |
550-790 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 550-790 of human OSBPL5 (NP_663613.1). |
| Immunogen Sequence: |
ALFWTPSGEVRRQRLRQHTV PLEEQTELESERLWQHVTRA ISKGDQHRATQEKFALEEAQ RQRARERQESLMPWKPQLFH LDPITQEWHYRYEDHSPWDP LKDIAQFEQDGILRTLQQEA VARQTTFLGSPGPRHERSGP DQRLRKASDQPSGHSQATES SGSTPESCPELSDEEQDGDF VPGGESPCPRCRKEARRLQA LHEAILSIREAQQELHRHLS AMLSSTARAAQAPTPGLLQ |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 5Orp-5Osbp-Related Protein 5Oxysterol-Binding Protein Homolog 1 |
| Database Links | Reactome: R-HSA-1482801 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs)Localizes To The Cortical Endoplasmic Reticulum At The Epcs |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 5 antibodyAnti-Orp-5 antibodyAnti-Osbp-Related Protein 5 antibodyAnti-Oxysterol-Binding Protein Homolog 1 antibodyAnti-OSBPL5 antibodyAnti-KIAA1534 antibodyAnti-OBPH1 antibodyAnti-ORP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
