| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OSBPL10 |
| Gene ID: | 114884 |
| Uniprot ID: | OSB10_HUMAN |
| Immunogen Region: | 200-400 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2). |
| Immunogen Sequence: | ASPCSQRHLSVGAPGVVTIT HHKSPAAARRAKSQYSGQLH EVREMMNQVEGQQKNLVHAI ESLPGSGPLTALDQDLLLLK ATSAATLSCLGECLNLLQQS VHQAGQPSQKPGASENILGW HGSKSHSTEQLKNGTLGSLP SASANITWAILPNSAEDEQT SQPEPEPNSGSELVLSEDEK SDNEDKEETELGVMEDQRSI I |
| Function | Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 10Orp-10Osbp-Related Protein 10 |
| Database Links | Reactome: R-HSA-1482801 |
| Cellular Localisation | CytoplasmCytoskeletonAssociates With Microtubules |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 10 antibodyAnti-Orp-10 antibodyAnti-Osbp-Related Protein 10 antibodyAnti-OSBPL10 antibodyAnti-ORP10 antibodyAnti-OSBP9 antibody |
Information sourced from Uniprot.org