• Western blot analysis of various lysates using OSBPL10 Rabbit polyclonal antibody (STJ115165) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-OSBPL10 antibody (200-400) (STJ115165)

SKU:
STJ115165

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-OSBPL10 (200-400) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OSBPL10
Gene ID: 114884
Uniprot ID: OSB10_HUMAN
Immunogen Region: 200-400
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human OSBPL10 (NP_060254.2).
Immunogen Sequence: ASPCSQRHLSVGAPGVVTIT HHKSPAAARRAKSQYSGQLH EVREMMNQVEGQQKNLVHAI ESLPGSGPLTALDQDLLLLK ATSAATLSCLGECLNLLQQS VHQAGQPSQKPGASENILGW HGSKSHSTEQLKNGTLGSLP SASANITWAILPNSAEDEQT SQPEPEPNSGSELVLSEDEK SDNEDKEETELGVMEDQRSI I
Function Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine.
Protein Name Oxysterol-Binding Protein-Related Protein 10
Orp-10
Osbp-Related Protein 10
Database Links Reactome: R-HSA-1482801
Cellular Localisation Cytoplasm
Cytoskeleton
Associates With Microtubules
Alternative Antibody Names Anti-Oxysterol-Binding Protein-Related Protein 10 antibody
Anti-Orp-10 antibody
Anti-Osbp-Related Protein 10 antibody
Anti-OSBPL10 antibody
Anti-ORP10 antibody
Anti-OSBP9 antibody

Information sourced from Uniprot.org

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