| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUP210 |
| Gene ID: | 23225 |
| Uniprot ID: | PO210_HUMAN |
| Immunogen Region: | 680-880 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 680-880 of human NUP210 (NP_079199.2). |
| Immunogen Sequence: | QNVTAEDTDSIGLALFAPHS SRNYQQHWILVTCQALGEQV IALSVGNKPSLTNPFPAVEP AVVKFVCAPPSRLTLAPVYT SPQLDMSCPLLQQNKQVVPV SSHRNPRLDLAAYDQEGRRF DNFSSLSIQWESTRPVLASI EPELPMQLVSQDDESGQKKL HGLQAILVHEASGTTAITAT ATGYQESHLSSARTKQPHDP L |
| Tissue Specificity | Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. |
| Post Translational Modifications | N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides. Phosphorylated at Ser-1881 in mitosis specifically.not phosphorylated in interphase. |
| Function | Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. |
| Protein Name | Nuclear Pore Membrane Glycoprotein 210 Nuclear Pore Protein Gp210 Nuclear Envelope Pore Membrane Protein Pom 210 Pom210 Nucleoporin Nup210 Pore Membrane Protein Of 210 Kda |
| Database Links | Reactome: R-HSA-1169408 Reactome: R-HSA-159227 Reactome: R-HSA-159230 Reactome: R-HSA-159231 Reactome: R-HSA-159236 Reactome: R-HSA-165054 Reactome: R-HSA-168271 Reactome: R-HSA-168276 Reactome: R-HSA-168325 Reactome: R-HSA-168333 Reactome: R-HSA-170822 Reactome: R-HSA-180746 Reactome: R-HSA-180910 Reactome: R-HSA-191859 Reactome: R-HSA-3108214 Reactome: R-HSA-3232142 Reactome: R-HSA-3301854 Reactome: R-HSA-3371453 Reactome: R-HSA-4085377 Reactome: R-HSA-4551638 Reactome: R-HSA-4570464 Reactome: R-HSA-4615885 Reactome: R-HSA-5578749 Reactome: R-HSA-5619107 Reactome: R-HSA-6784531 Reactome: R-HSA-9609690 Reactome: R-HSA-9610379 Reactome: R-HSA-9705671 |
| Cellular Localisation | Nucleus Nuclear Pore Complex Nucleus Membrane Single-Pass Type I Membrane Protein Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Nuclear Pore Membrane Glycoprotein 210 antibody Anti-Nuclear Pore Protein Gp210 antibody Anti-Nuclear Envelope Pore Membrane Protein Pom 210 antibody Anti-Pom210 antibody Anti-Nucleoporin Nup210 antibody Anti-Pore Membrane Protein Of 210 Kda antibody Anti-NUP210 antibody Anti-KIAA0906 antibody Anti-PSEC0245 antibody |
Information sourced from Uniprot.org