| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NT5C3A |
| Gene ID: | 51251 |
| Uniprot ID: | 5NT3A_HUMAN |
| Immunogen Region: | 37-336 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-336 of human NT5C3A (NP_001002010.1). |
| Immunogen Sequence: | TLKRKTGRKTKIIEMMPEFQ KSSVRIKNPTRVEEIICGLI KGGAAKLQIITDFDMTLSRF SYKGKRCPTCHNIIDNCKLV TDECRKKLLQLKEKYYAIEV DPVLTVEEKYPYMVEWYTKS HGLLVQQALPKAKLKEIVAE SDVMLKEGYENFFDKLQQHS IPVFIFSAGIGDVLEEVIRQ AGVYHPNVKVVSNFMDFDET GVLKGFKGELIHVFNKHDGA LRNTEYFNQLKDNSNIILL |
| Tissue Specificity | Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver. |
| Function | Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate. |
| Protein Name | Cytosolic 5'-Nucleotidase 3a 7-Methylguanosine Phosphate-Specific 5'-Nucleotidase 7-Methylguanosine Nucleotidase Cytosolic 5'-Nucleotidase 3 Cytosolic 5'-Nucleotidase Iii Cn-Iii Pyrimidine 5'-Nucleotidase 1 P5'N-1 P5n-1 Pn-I Uridine 5'-Monophosphate Hydrolase 1 P36 |
| Database Links | Reactome: R-HSA-73621 Q9H0P0-4 |
| Cellular Localisation | Cytoplasm Isoform 2: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cytosolic 5'-Nucleotidase 3a antibody Anti-7-Methylguanosine Phosphate-Specific 5'-Nucleotidase antibody Anti-7-Methylguanosine Nucleotidase antibody Anti-Cytosolic 5'-Nucleotidase 3 antibody Anti-Cytosolic 5'-Nucleotidase Iii antibody Anti-Cn-Iii antibody Anti-Pyrimidine 5'-Nucleotidase 1 antibody Anti-P5'N-1 antibody Anti-P5n-1 antibody Anti-Pn-I antibody Anti-Uridine 5'-Monophosphate Hydrolase 1 antibody Anti-P36 antibody Anti-NT5C3A antibody Anti-NT5C3 antibody Anti-P5N1 antibody Anti-UMPH1 antibody Anti-HSPC233 antibody |
Information sourced from Uniprot.org