Western blot analysis of extracts of various cell lines, using NRBP1 antibody (STJ112339) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-NRBP1 antibody (406-535) (STJ112339)

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STJ112339
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NRBP1
Gene ID: 29959
Uniprot ID: NRBP_HUMAN
Immunogen Region: 406-535
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1).
Immunogen Sequence: AFGLPRPQQPQQEEVTSPVV PPSVKTPTPEPAEVETRKVV LMQCNIESVEEGVKHHLTLL LKLEDKLNRHLSCDLMPNEN IPELAAELVQLGFISEADQS RLTSLLEETLNKFNFARNST LNSAAVTVSS
Tissue Specificity Ubiquitously expressed in all tissues examined with high levels in the testis.
Function Required for embryonic development. Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes. May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Protein Name Nuclear Receptor-Binding Protein
Database Links Reactome: R-HSA-383280
Cellular Localisation Cytoplasm
Cell Cortex
Endomembrane System
Cell Projection
Lamellipodium
Colocalizes With Activated Rac3 To Endomembranes And At The Cell Periphery In Lamellipodia
Alternative Antibody Names Anti-Nuclear Receptor-Binding Protein antibody
Anti-NRBP1 antibody
Anti-BCON3 antibody
Anti-NRBP antibody

Information sourced from Uniprot.org

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