| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NLGN3 |
| Gene ID: | 54413 |
| Uniprot ID: | NLGN3_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NLGN3 (Q9NZ94). |
| Immunogen Sequence: | MWLRLGPPSLSLSPKPTVGR SLCLTLWFLSLALRASTQAP APTVNTHFGKLRGARVPLPS EILGPVDQYLGVPYAAPPIG EKRFLPPEPPPSWSGIRNAT HFPPVCPQNIHTAVPEVMLP VWFTANLDIVATYIQEPNED CLYLNVYVPTEDVKRISKEC ARKPNKKICRKGGSGAKKQG EDLADNDGDEDEDIRDSGAK |
| Tissue Specificity | Expressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells. |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. |
| Protein Name | Neuroligin-3Gliotactin Homolog |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapseDetected At Both Glutamatergic And Gabaergic Synapses |
| Alternative Antibody Names | Anti-Neuroligin-3 antibodyAnti-Gliotactin Homolog antibodyAnti-NLGN3 antibodyAnti-KIAA1480 antibodyAnti-NL3 antibody |
Information sourced from Uniprot.org