| Tissue Specificity | Ubiquitous. |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. |
| Protein Name | Nhp2-Like Protein 1High Mobility Group-Like Nuclear Protein 2 Homolog 1Otk27Snu13 HomologHsnu13U4/U6.U5 Small Nuclear Ribonucleoprotein Snu13U4/U6.U5 Tri-Snrnp 15.5 Kda Protein Cleaved Into - Nhp2-Like Protein 1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolusConcentrated In The Dense Fibrillar Component Of The Nucleolus |
| Alternative Antibody Names | Anti-Nhp2-Like Protein 1 antibodyAnti-High Mobility Group-Like Nuclear Protein 2 Homolog 1 antibodyAnti-Otk27 antibodyAnti-Snu13 Homolog antibodyAnti-Hsnu13 antibodyAnti-U4/U6.U5 Small Nuclear Ribonucleoprotein Snu13 antibodyAnti-U4/U6.U5 Tri-Snrnp 15.5 Kda Protein Cleaved Into - Nhp2-Like Protein 1 - N-Terminally Processed antibodyAnti-SNU13 antibodyAnti-NHP2L1 antibody |
Information sourced from Uniprot.org
