Western blot analysis of lysates from NIH/3T3 cells, using PVRL4 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-NECTIN4 antibody (312-361) (STJ94390)

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STJ94390
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Nectin-4 (312-361) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NECTIN4
Gene ID: 81607
Uniprot ID: NECT4_HUMAN
Immunogen Region: 312-361
Specificity: Nectin 4 Polyclonal Antibody detects endogenous levels of Nectin 4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human PVRL4. AA range:312-361
Tissue Specificity Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.
Post Translational Modifications The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.
Protein Name Nectin-4
Ig Superfamily Receptor Lnir
Nectin Cell Adhesion Molecule 4
Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Colocalizes With Afdn At Cadherin-Based Adherens Junctions
Processed Poliovirus Receptor-Related Protein 4: Secreted
The Secreted Form Is Found In Breast Tumor Patients
Alternative Antibody Names Anti-Nectin-4 antibody
Anti-Ig Superfamily Receptor Lnir antibody
Anti-Nectin Cell Adhesion Molecule 4 antibody
Anti-Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 antibody
Anti-NECTIN4 antibody
Anti-LNIR antibody
Anti-PRR4 antibody
Anti-PVRL4 antibody

Information sourced from Uniprot.org

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