Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MYOZ1 |
Gene ID: | 58529 |
Uniprot ID: | MYOZ1_HUMAN |
Immunogen Region: | 180-299 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1). |
Immunogen Sequence: | VFKTYISPWERAMGVDPQQK MELGIDLLAYGAKAELPKYK SFNRTAMPYGGYEKASKRMT FQMPKFDLGPLLSEPLVLYN QNLSNRPSFNRTPIPWLSSG EPVDYNVDIGIPLDGETEEL |
Tissue Specificity | Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas. |
Function | Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
Protein Name | Myozenin-1Calsarcin-2Filamin- - Actinin- And Telethonin-Binding ProteinProtein Fatz |
Cellular Localisation | NucleusCell ProjectionPseudopodiumLocalized To The Nucleus And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated CellsColocalizes With Actn2Flnc And Myot At The Z-Lines Of Skeletal Muscle |
Alternative Antibody Names | Anti-Myozenin-1 antibodyAnti-Calsarcin-2 antibodyAnti-Filamin- - Actinin- And Telethonin-Binding Protein antibodyAnti-Protein Fatz antibodyAnti-MYOZ1 antibodyAnti-MYOZ antibody |
Information sourced from Uniprot.org