Anti-MUTYH antibody (476aa C-Term) (STJ140046)

SKU:
STJ140046
£99.50 - £373.50
Processing The item has been added

Host: Goat
Applications: WB
Reactivity: Human/Rat/Mouse/Monkey/Canine
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-MutY homolog (E. coli) (476aa C-Term) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 20% Glycerol and 0.05% Sodium Azide.
Purification: This antibody is epitope-affinity purified from goat antiserum.
Concentration: 3 mg/mL
Dilution Range: WB 1:500-1:2000
Ferreira JV Rosa Soares A Ramalho JS et al. PLoS One. 2019 Oct. PMID: 31613922
Storage Instruction: For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Gene Symbol: MUTYH
Gene ID: 4595
Uniprot ID: MUTYH_HUMAN
Immunogen Region: 476aa C-Term
Accession Number: ENSG00000132781
Specificity: In 293HEK cells transfected with cds plasmid (myc-his-Mutyh) detects a band of 50 kDa by Western blot.
Immunogen: Purified recombinant peptide derived from within residues 476 aa to the C-terminus of human Mutyh produced in E. coli.
Function Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Protein Name Adenine Dna Glycosylase
Muty Homolog
Hmyh
Database Links Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-110357
Reactome: R-HSA-9608287 Q9UIF7-3
Reactome: R-HSA-9608290
Cellular Localisation Nucleus
Mitochondrion
Alternative Antibody Names Anti-Adenine Dna Glycosylase antibody
Anti-Muty Homolog antibody
Anti-Hmyh antibody
Anti-MUTYH antibody
Anti-MYH antibody

Information sourced from Uniprot.org