| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MRM1 |
| Gene ID: | 79922 |
| Uniprot ID: | MRM1_HUMAN |
| Immunogen Region: | 1-353 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human MRM1 (NP_079140.2). |
| Immunogen Sequence: | MALLSTVRGATWGRLVTRHF SHAARHGERPGGEELSRLLL DDLVPTSRLELLFGMTPCLL ALQAARRSVARLLLQAGKAG LQGKRAELLRMAEARDIPVL RPRRQKLDTMCRYQVHQGVC MEVSPLRPRPWREAGEASPG DDPQQLWLVLDGIQDPRNFG AVLRSAHFLGVDKVITSRRN SCPLTPVVSKSSAGAMEVMD VFSTDDLTGFLQTKAQQGWL VAGTVGCPSTEDPQSSEIP |
| Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. |
| Protein Name | Rrna Methyltransferase 1 - Mitochondrial 16s Rrna Guanosine(1145-2'-O-Methyltransferase 16s Rrna Gm1145 2'-O-Methyltransferase |
| Database Links | Reactome: R-HSA-6793080 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Rrna Methyltransferase 1 - Mitochondrial antibody Anti-16s Rrna antibody Anti-Guanosine(1145-2'-O-Methyltransferase antibody Anti-16s Rrna Gm1145 2'-O-Methyltransferase antibody Anti-MRM1 antibody |
Information sourced from Uniprot.org
