• Western blot analysis of various lysates using MOGS Rabbit polyclonal antibody (STJ114598) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-MOGS antibody (60-320) (STJ114598)

SKU:
STJ114598

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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MOGS
Gene ID: 7841
Uniprot ID: MOGS_HUMAN
Immunogen Region: 60-320
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human MOGS (NP_006293.2).
Immunogen Sequence: RWVLAWYRARRAVTLHSAPP VLPADSSSPAVAPDLFWGTY RPHVYFGMKTRSPKPLLTGL MWAQQGTTPGTPKLRHTCEQ GDGVGPYGWEFHDGLSFGRQ HIQDGALRLTTEFVKRPGGQ HGGDWSWRVTVEPQDSGTSA LPLVSLFFYVVTDGKEVLLP EVGAKGQLKFISGHTSELGD FRFTLLPPTSPGDTAPKYGS YNVFWTSNPGLPLLTEMVKS RLNSWFQHRPPGAPPERYL
Function In the context of N-glycan degradation, cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner.
Protein Name Mannosyl-Oligosaccharide Glucosidase
Processing A-Glucosidase I
Database Links Reactome: R-HSA-4793954
Reactome: R-HSA-532668
Reactome: R-HSA-9683686
Reactome: R-HSA-9694548
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Mannosyl-Oligosaccharide Glucosidase antibody
Anti-Processing A-Glucosidase I antibody
Anti-MOGS antibody
Anti-GCS1 antibody

Information sourced from Uniprot.org

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