Anti-MLXIP antibody (50-150) (STJ119696)

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STJ119696
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MLXIP
Gene ID: 22877
Uniprot ID: MLXIP_HUMAN
Immunogen Region: 50-150
Specificity: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MLXIP (NP_055753.3).
Immunogen Sequence: ARAHASAAPPPPRAGPGREE PPRRQQIIHSGHFMVSSPHR EHPPKKGYDFDTVNKQTCQT YSFGKTSSCHLSIDASLTKL FECMTLAYSGKLVSPKWKNF K
Tissue Specificity Widely expressed in adult tissues. Most abundant in skeletal muscle.
Function Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Protein Name Mlx-Interacting Protein
Class E Basic Helix-Loop-Helix Protein 36
Bhlhe36
Transcriptional Activator Mondoa
Cellular Localisation Cytoplasm
Nucleus
Mitochondrion Outer Membrane
Predominantly Cytoplasmic But Shuttles Between Cytoplasm And Nucleus When Associated With Mlx
Also Associates With The Outer Mitochondrial Membrane And May Shuttle Between The Outer Mitochondrial Membrane And The Nucleus
Alternative Antibody Names Anti-Mlx-Interacting Protein antibody
Anti-Class E Basic Helix-Loop-Helix Protein 36 antibody
Anti-Bhlhe36 antibody
Anti-Transcriptional Activator Mondoa antibody
Anti-MLXIP antibody
Anti-BHLHE36 antibody
Anti-KIAA0867 antibody
Anti-MIR antibody
Anti-MONDOA antibody

Information sourced from Uniprot.org