Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MED13 (300-400) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MED13 |
Gene ID: |
9969 |
Uniprot ID: |
MED13_HUMAN |
Immunogen Region: |
300-400 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human MED13 (NP_005112.2). |
Immunogen Sequence: |
HCSSSCLGVHQVPASTRDPA MSSVTLTPPTSPEEVQTVDP QSVQKWVKFSSVSDGFNSDS TSHHGGKIPRKLANHVVDRV WQECNMNRAQNKRKYSASSG G |
Tissue Specificity | Ubiquitous. |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 13Activator-Recruited Cofactor 250 Kda ComponentArc250Mediator Complex Subunit 13Thyroid Hormone Receptor-Associated Protein 1Thyroid Hormone Receptor-Associated Protein Complex 240 Kda ComponentTrap240Vitamin D3 Receptor-Interacting Protein Complex Component Drip250Drip250 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 13 antibodyAnti-Activator-Recruited Cofactor 250 Kda Component antibodyAnti-Arc250 antibodyAnti-Mediator Complex Subunit 13 antibodyAnti-Thyroid Hormone Receptor-Associated Protein 1 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component antibodyAnti-Trap240 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex Component Drip250 antibodyAnti-Drip250 antibodyAnti-MED13 antibodyAnti-ARC250 antibodyAnti-KIAA0593 antibodyAnti-THRAP1 antibodyAnti-TRAP240 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance