Tissue Specificity | Ubiquitous. |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 13Activator-Recruited Cofactor 250 Kda ComponentArc250Mediator Complex Subunit 13Thyroid Hormone Receptor-Associated Protein 1Thyroid Hormone Receptor-Associated Protein Complex 240 Kda ComponentTrap240Vitamin D3 Receptor-Interacting Protein Complex Component Drip250Drip250 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 13 antibodyAnti-Activator-Recruited Cofactor 250 Kda Component antibodyAnti-Arc250 antibodyAnti-Mediator Complex Subunit 13 antibodyAnti-Thyroid Hormone Receptor-Associated Protein 1 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component antibodyAnti-Trap240 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex Component Drip250 antibodyAnti-Drip250 antibodyAnti-MED13 antibodyAnti-ARC250 antibodyAnti-KIAA0593 antibodyAnti-THRAP1 antibodyAnti-TRAP240 antibody |
Information sourced from Uniprot.org