| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GABRB1 (300-400) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GABRB1 |
| Gene ID: |
2560 |
| Uniprot ID: |
GBRB1_HUMAN |
| Immunogen Region: |
300-400 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human GABA A Receptor beta 1 (GABRB1) (NP_000803.2). |
| Immunogen Sequence: |
IPYVKAIDIYLMGCFVFVFL ALLEYAFVNYIFFGKGPQKK GASKQDQSANEKNKLEMNKV QVDAHGNILLSTLEIRNETS GSEVLTSVSDPKATMYSYDS A |
| Function | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital.these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
| Protein Name | Gamma-Aminobutyric Acid Receptor Subunit Beta-1Gaba(A Receptor Subunit Beta-1 |
| Database Links | Reactome: R-HSA-1236394Reactome: R-HSA-977443 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Gamma-Aminobutyric Acid Receptor Subunit Beta-1 antibodyAnti-Gaba(A Receptor Subunit Beta-1 antibodyAnti-GABRB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
