| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAZ (270-420) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAZ |
| Gene ID: |
4150 |
| Uniprot ID: |
MAZ_HUMAN |
| Immunogen Region: |
270-420 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 270-420 of human MAZ (NP_001036004.1). |
| Immunogen Sequence: |
ASGKRIRKNHACEMCGKAFR DVYHLNRHKLSHSDEKPYQC PVCQQRFKRKDRMSYHVRSH DGAVHKPYNCSHCGKSFSRP DHLNSHVRQVHSTERPFKCE KCEAAFATKDRLRAHTVRHE EKVPCHVCGKMLSSAYISDH MKVHSQGPHHV |
| Tissue Specificity | Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level). Isoform 1: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney. Expressed in the joint synovium. |
| Function | Transcriptional regulator, potentially with dual roles in transcription initiation and termination. Isoform 1: Binds DNA and functions as a transcriptional activator. Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Isoform 2: Binds DNA and functions as a transcriptional activator. Inhibits MAZ isoform 1-mediated transcription. Isoform 3: Binds DNA and functions as a transcriptional activator. |
| Protein Name | Myc-Associated Zinc Finger ProteinMaziPur-1Purine-Binding Transcription FactorSerum Amyloid A-Activating Factor-1Saf-1Transcription Factor Zif87Zf87Zinc Finger Protein 801 |
| Cellular Localisation | NucleusIn Brains Of Alzheimer Disease PatientsPresent In A Plaque-Like Structures |
| Alternative Antibody Names | Anti-Myc-Associated Zinc Finger Protein antibodyAnti-Mazi antibodyAnti-Pur-1 antibodyAnti-Purine-Binding Transcription Factor antibodyAnti-Serum Amyloid A-Activating Factor-1 antibodyAnti-Saf-1 antibodyAnti-Transcription Factor Zif87 antibodyAnti-Zf87 antibodyAnti-Zinc Finger Protein 801 antibodyAnti-MAZ antibodyAnti-ZNF801 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
