Post Translational Modifications | The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis. |
Function | Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments. |
Protein Name | EnsconsinEpithelial Microtubule-Associated Protein Of 115 KdaE-Map-115Microtubule-Associated Protein 7Map-7 |
Cellular Localisation | CytoplasmPerinuclear RegionBasolateral Cell MembraneCytoskeletonColocalized On MicrotubulesAn Intracellular Redistribution Is Triggered During Induction Of Keratinocyte Terminal Differentiation From Microtubules With A Perinuclear Localization To Cortical Microtubules Organized In Spike-Like Bundles Facing Intercellular Contacts |
Alternative Antibody Names | Anti-Ensconsin antibodyAnti-Epithelial Microtubule-Associated Protein Of 115 Kda antibodyAnti-E-Map-115 antibodyAnti-Microtubule-Associated Protein 7 antibodyAnti-Map-7 antibodyAnti-MAP7 antibody |
Information sourced from Uniprot.org