| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LYPLAL1 |
| Gene ID: |
127018 |
| Uniprot ID: |
LYPL1_HUMAN |
| Immunogen Region: |
1-100 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LYPLAL1 (NP_620149.2). |
| Immunogen Sequence: |
MAAASGSVLQRCIVSPAGRH SASLIFLHGSGDSGQGLRMW IKQVLNQDLTFQHIKIIYPT APPRSYTPMKGGISNVWFDR FKITNDCPEHLESIDVMCQV |
| Function | Palmitoyl thioesterase that catalyzes depalmitoylation of CGAS and KCNMA1. Acts as a regulator of innate immunity by mediating depalmitoylation of CGAS, thereby preventing CGAS homodimerization and cyclic GMP-AMP synthase activity. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site. |
| Protein Name | Lysophospholipase-Like Protein 1 |
| Cellular Localisation | Isoform 1: CytoplasmCytosolIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Lysophospholipase-Like Protein 1 antibodyAnti-LYPLAL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
