| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LTB4R2 (254-358) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LTB4R2 |
| Gene ID: |
56413 |
| Uniprot ID: |
LT4R2_HUMAN |
| Immunogen Region: |
254-358 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2). |
| Immunogen Sequence: |
PPEGALAKLGGAGQAARAGT TALAFFSSSVNPVLYVFTAG DLLPRAGPRFLTRLFEGSGE ARGGGRSREGTMELRTTPQL KVVGQGRGNGDPGGGMEKDG PEWDL |
| Tissue Specificity | Widely expressed. |
| Function | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. |
| Protein Name | Leukotriene B4 Receptor 2Ltb4-R 2Ltb4-R2Ltb4 Receptor Julf2Leukotriene B4 Receptor Blt2Seven Transmembrane Receptor Bltr2 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 2 antibodyAnti-Ltb4-R 2 antibodyAnti-Ltb4-R2 antibodyAnti-Ltb4 Receptor Julf2 antibodyAnti-Leukotriene B4 Receptor Blt2 antibodyAnti-Seven Transmembrane Receptor Bltr2 antibodyAnti-LTB4R2 antibodyAnti-BLT2R antibodyAnti-BLTR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
