| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LTB4R2 |
| Gene ID: | 56413 |
| Uniprot ID: | LT4R2_HUMAN |
| Immunogen Region: | 254-358 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2). |
| Immunogen Sequence: | PPEGALAKLGGAGQAARAGT TALAFFSSSVNPVLYVFTAG DLLPRAGPRFLTRLFEGSGE ARGGGRSREGTMELRTTPQL KVVGQGRGNGDPGGGMEKDG PEWDL |
| Tissue Specificity | Widely expressed. |
| Function | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. |
| Protein Name | Leukotriene B4 Receptor 2Ltb4-R 2Ltb4-R2Ltb4 Receptor Julf2Leukotriene B4 Receptor Blt2Seven Transmembrane Receptor Bltr2 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 2 antibodyAnti-Ltb4-R 2 antibodyAnti-Ltb4-R2 antibodyAnti-Ltb4 Receptor Julf2 antibodyAnti-Leukotriene B4 Receptor Blt2 antibodyAnti-Seven Transmembrane Receptor Bltr2 antibodyAnti-LTB4R2 antibodyAnti-BLT2R antibodyAnti-BLTR2 antibody |
Information sourced from Uniprot.org