• Western blot analysis of various lysates using LAGE3 Rabbit polyclonal antibody (STJ11103371) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-LAGE3 antibody (1-143) (STJ11103371)

SKU:
STJ11103371

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LAGE3 (1-143) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LAGE3
Gene ID: 8270
Uniprot ID: LAGE3_HUMAN
Immunogen Region: 1-143
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2).
Immunogen Sequence: MRDADADAGGGADGGDGRGG HSCRGGVDTAAAPAGGAPPA HAPGPGRDAASAARGSRMRP HIFTLSVPFPTPLEAEIAHG SLAPDAEPHQRVVGKDLTVS GRILVVRWKAEDCRLLRISV INFLDQLSLVVRTMQRFGPP VSR
Tissue Specificity Ubiquitous.
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
Protein Name Ekc/Keops Complex Subunit Lage3
L Antigen Family Member 3
Protein Eso-3
Protein Itba2
Database Links Reactome: R-HSA-6782315
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Ekc/Keops Complex Subunit Lage3 antibody
Anti-L Antigen Family Member 3 antibody
Anti-Protein Eso-3 antibody
Anti-Protein Itba2 antibody
Anti-LAGE3 antibody
Anti-DXS9879E antibody
Anti-ESO3 antibody
Anti-ITBA2 antibody

Information sourced from Uniprot.org

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