Western blot analysis of extracts of various cell lines, using KIR3DL2 antibody (STJ112156) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-KIR3DL2 antibody (361-455) (STJ112156)

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STJ112156
£112.50 - £524.50
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIR3DL2
Gene ID: 3812
Uniprot ID: KI3L2_HUMAN
Immunogen Region: 361-455
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 361-455 of human KIR3DL2 (NP_006728.2).
Immunogen Sequence: YRWCSNKKNAAVMDQEPAGD RTVNRQDSDEQDPQEVTYAQ LDHCVFIQRKISRPSQRPKT PLTDTSVYTELPNAEPRSKV VSCPRAPQSGLEGVF
Tissue Specificity Expressed in astrocytes.
Function Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.
Protein Name Killer Cell Immunoglobulin-Like Receptor 3dl2
Cd158 Antigen-Like Family Member K
Natural Killer-Associated Transcript 4
Nkat-4
P70 Natural Killer Cell Receptor Clone Cl-5
P70 Nk Receptor Cl-5
Cd Antigen Cd158k
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Killer Cell Immunoglobulin-Like Receptor 3dl2 antibody
Anti-Cd158 Antigen-Like Family Member K antibody
Anti-Natural Killer-Associated Transcript 4 antibody
Anti-Nkat-4 antibody
Anti-P70 Natural Killer Cell Receptor Clone Cl-5 antibody
Anti-P70 Nk Receptor Cl-5 antibody
Anti-Cd Antigen Cd158k antibody
Anti-KIR3DL2 antibody
Anti-CD158K antibody
Anti-NKAT4 antibody

Information sourced from Uniprot.org

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