| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIF5C |
| Gene ID: | 3800 |
| Uniprot ID: | KIF5C_HUMAN |
| Immunogen Region: | 510-590 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1). |
| Immunogen Sequence: | RANEQLTDELAQKTTTLTTT QRELSQLQELSNHQKKRATE ILNLLLKDLGEIGGIIGTND VKTLADVNGVIEEEFTMARL Y |
| Tissue Specificity | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary. |
| Function | Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity. Involved in synaptic transmission. Mediates dendritic trafficking of mRNAs. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
| Protein Name | Kinesin Heavy Chain Isoform 5cKinesin Heavy Chain Neuron-Specific 2Kinesin-1 |
| Database Links | Reactome: R-HSA-264876 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionDendriteAbundant In Distal Regions Of Dendrites |
| Alternative Antibody Names | Anti-Kinesin Heavy Chain Isoform 5c antibodyAnti-Kinesin Heavy Chain Neuron-Specific 2 antibodyAnti-Kinesin-1 antibodyAnti-KIF5C antibodyAnti-KIAA0531 antibodyAnti-NKHC2 antibody |
Information sourced from Uniprot.org