| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIF5C (510-590) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIF5C |
| Gene ID: |
3800 |
| Uniprot ID: |
KIF5C_HUMAN |
| Immunogen Region: |
510-590 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 510-590 of human KIF5C (NP_004513.1). |
| Immunogen Sequence: |
RANEQLTDELAQKTTTLTTT QRELSQLQELSNHQKKRATE ILNLLLKDLGEIGGIIGTND VKTLADVNGVIEEEFTMARL Y |
| Tissue Specificity | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary. |
| Function | Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity. Involved in synaptic transmission. Mediates dendritic trafficking of mRNAs. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
| Protein Name | Kinesin Heavy Chain Isoform 5cKinesin Heavy Chain Neuron-Specific 2Kinesin-1 |
| Database Links | Reactome: R-HSA-264876 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionDendriteAbundant In Distal Regions Of Dendrites |
| Alternative Antibody Names | Anti-Kinesin Heavy Chain Isoform 5c antibodyAnti-Kinesin Heavy Chain Neuron-Specific 2 antibodyAnti-Kinesin-1 antibodyAnti-KIF5C antibodyAnti-KIAA0531 antibodyAnti-NKHC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
