| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNK4 (25-90) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNK4 |
| Gene ID: |
50801 |
| Uniprot ID: |
KCNK4_HUMAN |
| Immunogen Region: |
25-90 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-90 of human KCNK4 (NP_201567.1). |
| Immunogen Sequence: |
RALEQPHEQQAQRELGEVRE KFLRAHPCVSDQELGLLIKE VADALGGGADPETNSTSNSS HSAWDL |
| Post Translational Modifications | N-glycosylated. |
| Function | Voltage-insensitive potassium channel. Channel opening is triggered by mechanical forces that deform the membrane. Channel opening is triggered by raising the intracellular pH to basic levels. The channel is inactive at 24 degrees Celsius (in vitro).raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius. Plays a role in the perception of pain caused by heat. Plays a role in the sensory perception of pain caused by pressure. |
| Protein Name | Potassium Channel Subfamily K Member 4Twik-Related Arachidonic Acid-Stimulated Potassium Channel ProteinTraakTwo Pore Potassium Channel Kt4.1Two Pore K(+ Channel Kt4.1 |
| Database Links | Reactome: R-HSA-1299503Reactome: R-HSA-5576886 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily K Member 4 antibodyAnti-Twik-Related Arachidonic Acid-Stimulated Potassium Channel Protein antibodyAnti-Traak antibodyAnti-Two Pore Potassium Channel Kt4.1 antibodyAnti-Two Pore K(+ Channel Kt4.1 antibodyAnti-KCNK4 antibodyAnti-TRAAK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
