Anti-KCNIP2 antibody (N-Term) (STJ13101296)

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STJ13101296-100
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-KCNIP2 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: KCNIP2
Gene ID: 30819
Uniprot ID: KCIP2_HUMAN
Immunogen Region: N-Term
Specificity: Specific for KCNIP2.
Immunogen: A synthetic peptide from n-terminal region of mouse KCNIP2 (Potassium channel-interacting protein 2) conjugated to an immunogenic carrier protein was used as the antigen.
Post Translational Modifications Palmitoylated. Palmitoylation enhances association with the plasma membrane.
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart.
Protein Name A-Type Potassium Channel Modulatory Protein Kcnip2
Cardiac Voltage-Gated Potassium Channel Modulatory Subunit
Kv Channel-Interacting Protein 2
Kchip2
Potassium Channel-Interacting Protein 2
Database Links Reactome: R-HSA-5576894
Cellular Localisation Isoform 1: Cell Membrane
Lipid-Anchor
Detected On Lipid Rafts
Isoform 2: Cell Membrane
Isoform 6: Cell Membrane
Alternative Antibody Names Anti-A-Type Potassium Channel Modulatory Protein Kcnip2 antibody
Anti-Cardiac Voltage-Gated Potassium Channel Modulatory Subunit antibody
Anti-Kv Channel-Interacting Protein 2 antibody
Anti-Kchip2 antibody
Anti-Potassium Channel-Interacting Protein 2 antibody
Anti-KCNIP2 antibody
Anti-KCHIP2 antibody

Information sourced from Uniprot.org

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