| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNIP1 (1-216) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNIP1 |
| Gene ID: |
30820 |
| Uniprot ID: |
KCIP1_HUMAN |
| Immunogen Region: |
1-216 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human KCNIP1 (NP_055407.1). |
| Immunogen Sequence: |
MGAVMGTFSSLQTKQRRPSK DKIEDELEMTMVCHRPEGLE QLEAQTNFTKRELQVLYRGF KNECPSGVVNEDTFKQIYAQ FFPHGDASTYAHYLFNAFDT TQTGSVKFEDFVTALSILLR GTVHEKLRWTFNLYDINKDG YINKEEMMDIVKAIYDMMGK YTYPVLKEDTPRQHVDVFFQ KMDKNKDGIVTLDEFLESCQ EDDNIMRSLQLFQNVM |
| Tissue Specificity | Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus. |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface. |
| Protein Name | Kv Channel-Interacting Protein 1Kchip1A-Type Potassium Channel Modulatory Protein 1Potassium Channel-Interacting Protein 1Vesicle Apc-Binding Protein |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Kv Channel-Interacting Protein 1 antibodyAnti-Kchip1 antibodyAnti-A-Type Potassium Channel Modulatory Protein 1 antibodyAnti-Potassium Channel-Interacting Protein 1 antibodyAnti-Vesicle Apc-Binding Protein antibodyAnti-KCNIP1 antibodyAnti-KCHIP1 antibodyAnti-VABP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
